Causes of Epidermolysis Bullosa
Epidermolysis bullosa can be inherited both in a dominant (the patient has a 50:50 chance of getting it from a single affected parent) or recessive pattern (one affected gene needs to be present from both parents). The inherited defect causes a weakening in various parts of the skin structure, resulting in skin that is more fragile and susceptible to internal splitting and blister formation.
The closely related form, epidermolysis bullosa acquisita, displays evidence of immune dysfunction (i.e., the patient's own immune system attacks the body) and possible genetic transmission.
Physician-developed and -monitored.
Original Date of Publication: 01 Sep 2000
Reviewed by: Stanley J. Swierzewski, III, M.D.
Last Reviewed:
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