Overview of Fifth Disease
Erythema infectiosum, also known as fifth disease, is a viral infection that mainly occurs in childhood, usually as an epidemic associated with outbreaks in schools.
Cause of Fifth Disease
Erythema infectiosum is caused by parvovirus B19. It is believed to be primarily transmitted by the respiratory route (the B19 virus has been isolated from respiratory secretions during the contagious phase). Once the rash appears, the child is no longer contagious. About one-half of adults are immune to the infection due to previous exposure.
Physician-developed and -monitored.
Original Date of Publication: 01 Sep 2000
Reviewed by: Stanley J. Swierzewski, III, M.D.
Last Reviewed: 04 Dec 2007
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